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The C8 nerve contributes to the motor innervation of many of the muscles in the trunk and upper limb. Its primary function is the flexion of the fingers, and this is used as the clinical test for C8 integrity, in conjunction with the finger jerk reflex.
The ciliospinal center (also known as Budge's center [1]) is a cluster of [citation needed] pre-ganglionic sympathetic neuron cell bodies located in the intermediolateral cell column (of the cornu laterale) at spinal cord segment (C8: Anatomic variation) T1-T2 [2]
The brachial plexus is a network of nerves (nerve plexus) formed by the anterior rami of the lower four cervical nerves and first thoracic nerve (C5, C6, C7, C8, and T1).This plexus extends from the spinal cord, through the cervicoaxillary canal in the neck, over the first rib, and into the armpit, it supplies afferent and efferent nerve fibers to the chest, shoulder, arm, forearm, and hand.
This is in contrast with the dorsal spinocerebellar tract (C8 - L2/L3), which only has 1 unilateral axon that has its cell body in Clarke's column (only at the level of C8 - L2/L3). Originates from ventral horn at lumbosacral spinal levels. Axons first cross midline in the spinal cord and run in the ventral border of the lateral funiculi.
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The spinal accessory nucleus lies within the cervical spinal cord (C1-C5) in the posterolateral aspect of the anterior horn. The nucleus ambiguus is classically said to provide the "cranial component" of the accessory nerve .
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Klumpke's paralysis is a variety of partial palsy of the lower roots of the brachial plexus. [1] [2] The brachial plexus is a network of spinal nerves that originates in the back of the neck, extends through the axilla (armpit), and gives rise to nerves to the upper limb.