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Vickers is known for his research into prostate cancer screening. [6] In 2011, he published a study which found that PSA velocity—the change in the blood level of prostate-specific antigen (PSA)--was not a more accurate predictor of prostate cancer than comparing PSA levels to a specific threshold. [7]
In 1993, he developed the PartinTables to help prostate cancer patients get an accurate prediction of their likelihood of being cured. The tables originally did not include the Gleason score and were based only on prostate-specific antigen (PSA) and tumor, node, and metastases.
PSA based screening and treatment of prostate cancer at a localized stage can prevent prostate cancer death for some men. [ 7 ] [ 10 ] However, if curative intervention is the downstream consequence of every screen detected prostate cancer, a large proportion of men will undergo unnecessary treatment and experience functional declines in ...
The Prostate Health Index (PHI) is a PSA-based blood test for early prostate cancer screening. It may be used to determine when a biopsy is needed. [32] [46] Prostate cancer antigen 3 is a urine test that detects the overexpression of the PCA3 gene, an indicator of prostate cancer. [32] [46] [47] [44]
SimBioSys anticipates FDA clearance for its breast cancer surgical planning tool in late 2023 with an expansion to other solid tumors to follow. Validation to lung and prostate cancer is already underway. While awaiting FDA approval, SimBioSys is commercializing the technology for use in patient education and drug development.
The mRNA-based disease diagnosis technologies have been applied to medical field widely in recent years, especially on early diagnosis of tumors (such as renal cell carcinoma, [2] hepatocellular carcinoma, [3] [4] breast cancer [5] and prostate cancer [6]). The technology can be applied to various types of samples depending on how easily the ...
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