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Pergolide acts on many of the same receptors as dopamine to increase receptor activity. It was patented in 1978 [3] and approved for medical use in 1989. [4] In 2007, pergolide was withdrawn from the U.S. market for human use after several published studies revealed a link between the drug and increased rates of valvular heart disease. [5]
Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, [ 1 ] and is classically associated with the formation of a long, wavy coat ( hirsutism ) and chronic laminitis .
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This article is within the scope of WikiProject Equine, a collaborative effort to improve Wikipedia's coverage of articles relating to horses, asses, zebras, hybrids, equine health, equine sports, etc. Please visit the project page for details or ask questions at the barn. Equine Wikipedia:WikiProject Equine Template:WikiProject Equine equine: Low
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