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The apical ectodermal ridge (AER) is a structure that forms from the ectodermal cells at the distal end of each limb bud and acts as a major signaling center to ensure proper development of a limb. After the limb bud induces AER formation, the AER and limb mesenchyme —including the zone of polarizing activity (ZPA)—continue to communicate ...
The ZPA forms where the Hox8 region joins the AER. These regions are dependent on signaling in order for the appropriate induction events to occur. The AER expresses FGF8 which induces Shh expression in the posterior mesoderm. Shh then stimulates FGF4 to be expressed in the posterior part of the AER. After these events, there is a co-dependence ...
Complex communication ensues as AER-secreted FGF signals and ZPA-secreted Shh signals initiate and regulate Hox gene expression in the developing limb bud. [18] Though many of the finer details remain to be resolved, a number of significant connections between Hox gene expression and the impact on limb development have been discovered.
Seal of the Army Emergency Relief. Army Emergency Relief (AER) is a non-profit, charitable organization independent of, but closely associated with the United States Army.AER was established on Feb. 5, 1943, in Washington, DC, by Secretary of War Henry Stinson and Army Chief of Staff Gen. George Marshall, with $1.5 million in seed money from the American Red Cross and $12 million from Irving ...
The AER is essential for the distal patterning of the limb. Experiments executed in chicken models show Radical fringe is expressed in both the dorsal ectoderm and the AER. This provides evidence that the AER forms from cells already expressing radical fringe, though further evidence is needed to confirm.
Free File Fillable Forms is an electronic version of IRS paper forms. Free File Fillable Forms does not include any elaborate cross-checking or question-and-answer formats (such as is found in many of the Free File Software packages), instead it is a simple fill-in-the blank format (however, it does perform math calculations).
An enlisted evaluation report (EER) is an evaluation form used by the United States Army; the US Coast Guard also uses a document of the same title. The Army commissioned officer equivalent is the officer evaluation report (OER). The United States Navy equivalent is the fitness report (FITREP
AER Alaska Central Express: ACE AIR United States AAK Alaska Island Air: ALASKA ISLAND United States KH AAH Aloha Air Cargo: ALOHA United States AQ AAH Aloha Airlines: ALOHA United States defunct; former IATA code: TS AA AAL American Airlines: AMERICAN United States XFS American Flight Service Systems: United States XMG AMS Group: Russia WD* AAN