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Top: An ancestral gene duplication produces two paralogs (histone H1.1 and 1.2). A speciation event produces orthologs in the two daughter species (human and chimpanzee). Bottom: in a separate species , a gene has a similar function (histone-like nucleoid-structuring protein) but has a separate evolutionary origin and so is an analog.
Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase, and is a key player in cell cycle regulation. [5]
English: Levels of the three major cyclin types oscillate during the cell cycle (top), providing the basis for oscillations in the cyclin–Cdk complexes that drive cell-cycle events (bottom). In general, Cdk levels are constant and in large excess over cyclin levels; thus, cyclin–Cdk complexes form in parallel with cyclin levels.
18626 Ensembl ENSG00000179094 ENSMUSG00000020893 UniProt O15534 O35973 RefSeq (mRNA) NM_002616 NM_001159367 NM_011065 RefSeq (protein) NP_002607 NP_001152839 NP_035195 Location (UCSC) Chr 17: 8.14 – 8.16 Mb Chr 11: 68.99 – 69 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Period circadian protein homolog 1 is a protein in humans that is encoded by the PER1 gene. Function The ...
Double-stranded RNA-binding protein Staufen homolog 1 is a protein that in humans is encoded by the STAU1 gene. [5] [6] [7]Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles.
In Hyphomicrobiales and Enterobacteriales, syntenic genes encode a large number of essential cell functions and represent a high level of functional relationships. [ 15 ] Patterns of shared synteny or synteny breaks can also be used as characters to infer the phylogenetic relationships among several species, and even to infer the genome ...
The human homolog (DHH) is on chromosome band 12q13.1. [ 5 ] [ 6 ] The protein encoded by this gene is involved in cell signaling . The several mammalian variants of the Drosophila hedgehog gene ( which was the first named ) have been named after the various species of hedgehog ; the desert hedgehog is honored by this one.
The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [6] In yeasts, the Dom34-Hbs1 complex (with ABCE1) that it forms is responsible for reactivating ribosomes and for recovering those stuck on mRNAs. [7] It is a paralog of the release factor eRF1. The Drosophila homolog was first discovered ...