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Unethical human experimentation is human experimentation that violates the principles of medical ethics. Such practices have included denying patients the right to informed consent , using pseudoscientific frameworks such as race science , and torturing people under the guise of research.
A subject of the Tuskegee syphilis experiment has his blood drawn, c. 1953.. Numerous experiments which were performed on human test subjects in the United States in the past are now considered to have been unethical, because they were performed without the knowledge or informed consent of the test subjects. [1]
Beecher's findings were not alone. Evidence emerged that soon after the introduction of nuclear weapons, soldiers and civilians were subjected to potentially dangerous levels of radiation – without consent – to test its health effects (see Advisory Committee on Human Radiation Experiments and human radiation experiments in the United States).
Nazi human experimentation – Unethical experiments on human subjects; Non-human primate experiments – Experimentation using other primate animals; Statistical unit – Individual entity for statistical purposes; Unethical human experimentation in the United States – Experiments that were performed on humans in the US that are deemed unethical
In response to the criticism of unethical human experimentation, the Weimar Republic (Germany's government from 1919 to 1933) issued "Guidelines for New Therapy and Human Experimentation". The guidelines were based on beneficence and non-maleficence , but also stressed the legal doctrine of informed consent .
One of the earliest models for ethical human experimentation, preceding the Nuremberg Code, was established in 1931. [4] In the Weimar Republic of 20th century pre-Nazi Germany, the entity known as Reichsgesundheitsamt [5] (translating roughly to National Health Service), under the Ministry of the Interior [6] formulated a list of 14 points detailing these ethical principles.
More than 12,000 untested kits had been found in Los Angeles County as of 2009, according to Human Rights Watch. Gerardo Cabanillas, left, was exonerated in 2023, after being locked up for 28 years.
The Declaration of Helsinki (DoH, Finnish: Helsingin julistus) is a set of ethical principles regarding human experimentation developed originally in 1964 for the medical community by the World Medical Association (WMA). [1] It is widely regarded as the cornerstone document on human research ethics. [1] [2] [3] [4]