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Hydroxycarboxylic acid receptor 3 (HCA 3), also known as niacin receptor 2 (NIACR2) and GPR109B, [5] is a protein which in humans is encoded by the HCAR3 gene. [ 6 ] [ 7 ] HCA 3 , like the other hydroxycarboxylic acid receptors HCA 1 and HCA 2 , is a G i/o -coupled G protein-coupled receptor (GPCR).
3-Hydroxyoctanoic acid is a beta-hydroxy acid that is naturally produced in humans, other animals, and plants. 3-Hydroxyoctanoic acid is the primary endogenous agonist of hydroxycarboxylic acid receptor 3 (HCA 3 ), a G protein-coupled receptor protein which is encoded by the human gene HCAR3 .
The hydroxycarboxylic acid receptor (abbreviated HCA receptor and HCAR) family includes the following human proteins: [1] Hydroxycarboxylic acid receptor 1 (HCA 1 , formerly known as GPR81) Hydroxycarboxylic acid receptor 2 (HCA 2 , formerly known as niacin receptor 1 and GPR109A)
HCA 2 is expressed by: 1) certain cells in the immune system, e.g., neutrophils, monocytes, macrophages, dermal dendritic cells, [18] and lymphocytes; [13] 2) cells in the small intestine and colon epithelum that face the intestinal lumen; [26] 3) the skin's epithelial cells, keratinocytes, and Langerhans cells; [27] 4) brown and white adipose tissue fat cells; [28] 5) cells in the mammary ...
Hydroxycarboxylic acid receptor 1 (HCA 1), formerly known as G protein-coupled receptor 81 (GPR81), is a protein that in humans is encoded by the HCAR1 gene. [ 5 ] [ 6 ] HCA 1 , like the other hydroxycarboxylic acid receptors HCA 2 and HCA 3 , is a G i/o -coupled G protein-coupled receptor (GPCR).
A corrections officer at an Ohio prison was killed Christmas day when an inmate attacked him, authorities said Wednesday.. The assault occurred Wednesday morning at the Ross Correctional ...
Certain types of headaches may be a sign of a more serious condition, such as a brain tumor or aneurysm, especially if the pain is sudden or severe, according to Cohen. "This highlights the ...
Cross-platform open-source desktop search engine. Unmaintained since 2011-06-02 [9]. LGPL v2 [10] Terrier Search Engine: Linux, Mac OS X, Unix: Desktop search for Windows, Mac OS X (Tiger), Unix/Linux. MPL v1.1 [11] Tracker: Linux, Unix: Open-source desktop search tool for Unix/Linux GPL v2 [12] Tropes Zoom: Windows: Semantic Search Engine (no ...