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Cimetidine, sold under the brand name Tagamet among others, is a histamine H 2 receptor antagonist that inhibits stomach acid production. [1] [9] [10] It is mainly used in the treatment of heartburn and peptic ulcers. [1] [10] [11]
Home remedies are an inexpensive and accessible way to treat heartburn pain. If the first remedy doesn’t help, keep trying—eventually, one of these options will likely work for you.
Heartburn can be extremely uncomfortable, but is actually very common nowadays. WebMD writes, "The prevalence of weekly heartburn and other symptoms of acid reflux rose nearly 50 percent over the ...
To put this into perspective, some research shows that reducing your systolic blood pressure (top blood pressure reading) by 5 mmHg may lower your risk of cardiovascular events by 10%! The Bottom Line
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
Functional heartburn is heartburn of unknown cause. [24] It is commonly associated with psychiatric conditions like depression and anxiety. It is also seen with other functional gastrointestinal disorders like irritable bowel syndrome and is the primary cause of lack of improvement post treatment with proton pump inhibitors (PPIs). [24]
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