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The coma cocktail is thought to have been created in United States as a first line treatment for an unconscious patient in an era where intensive care was new and difficult to maintain. Original coma cocktails included methylxanthines , physostigmine , physical stimulation (such as cold water baths or ammonium carbonate (" smelling salts ...
Dr. Gerard Carroll, an associate professor of emergency medicine at Cooper Medical School in Camden and co-author of the study, said the data also shows that 100% of overdose patients who accepted ...
Opioid overdose deaths have grown much faster than other overdose deaths. In 2020 in Benton and Franklin counties the rate was 15.3 people per 100,000, or about 46 people that year. It’s close ...
Opiate overdose symptoms and signs can be referred to as the "opioid toxidrome triad": decreased level of consciousness, pinpoint pupils and respiratory depression. Other symptoms include seizures and muscle spasms. Sometimes an opiate overdose can lead to such a decreased level of consciousness such that the person will not wake up.
Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death.
Drug detoxification (informally, detox) is variously construed or interpreted as a type of "medical" intervention or technique in regards to a physical dependence mediated by a drug; as well as the process and experience of a withdrawal syndrome or any of the treatments for acute drug overdose (toxidrome).
The hope is that it will trigger a rush of clinical trial testing for drug treatments for stimulant use disorder, aiming to fill a major gap in the response to the overdose crisis in the U.S.
Drug overdose was the leading cause of injury death in 2013. Among people 25 to 64 years old, drug overdose caused more deaths than motor vehicle traffic crashes. There were 43,982 drug overdose deaths in the United States in 2013. Of these, 22,767 (51.8%) were related to prescription drugs. [33]