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Liposomes that contain low (or high) pH can be constructed such that dissolved aqueous drugs will be charged in solution (i.e., the pH is outside the drug's pI range). As the pH naturally neutralizes within the liposome ( protons can pass through some membranes), the drug will also be neutralized, allowing it to freely pass through a membrane.
Salt metathesis is often employed to obtain salts that are soluble in organic solvents. Illustrative is the conversion of sodium perrhenate to the tetrabutylammonium salt: [2] NaReO 4 + N(C 4 H 9) 4 Cl → N(C 4 H 9) 4 [ReO 4] + NaCl. The tetrabutylammonium salt precipitates from the aqueous solution. It is soluble in dichloromethane.
The human body and even its individual body fluids may be conceptually divided into various fluid compartments, which, although not literally anatomic compartments, do represent a real division in terms of how portions of the body's water, solutes, and suspended elements are segregated. The two main fluid compartments are the intracellular and ...
Cross-sectional view of the structures that can be formed by phospholipids in an aqueous solution. A biological membrane, biomembrane or cell membrane is a selectively permeable membrane that separates the interior of a cell from the external environment or creates intracellular compartments by serving as a boundary between one part of the cell and another.
An aqueous solution is a solution in which the solvent is water. It is mostly shown in chemical equations by appending (aq) to the relevant chemical formula . For example, a solution of table salt , also known as sodium chloride (NaCl), in water would be represented as Na + (aq) + Cl − (aq) .
It is a logarithmic scale used to specify the acidity or basicity of aqueous solutions. Acidic solutions (solutions with higher concentrations of hydrogen (H +) ions) are measured to have lower pH values than basic or alkaline solutions. The pH scale is logarithmic and inversely indicates the activity of hydrogen ions in the solution
It is essentially an aqueous solution containing 92% water, 8% blood plasma proteins, and trace amounts of other materials. Plasma circulates dissolved nutrients, such as glucose , amino acids , and fatty acids (dissolved in the blood or bound to plasma proteins), and removes waste products, such as carbon dioxide , urea , and lactic acid .
Their primary role is to maintain the integrity of cells by affecting the viscosity, melting point, and ionic strength of the aqueous solution. When a cell swells due to external osmotic pressure , membrane channels open and allow efflux of osmolytes carrying water, restoring normal cell volume.