Search results
Results from the WOW.Com Content Network
In medicine, salpingo-oophorectomy is the removal of an ovary and its fallopian tube. [1] [2] This procedure is most frequently associated with prophylactic surgery in response to the discovery of a BRCA mutation, particularly those of the normally tumor suppressing BRCA1 gene (or, with a statistically lower negative impact, those of the tumour suppressing BRCA2 gene), which can increase the ...
Most bilateral oophorectomies (63%) are performed without any medical indication, and most (87%) are performed together with a hysterectomy. [10] Conversely, unilateral oophorectomy is commonly performed for a medical indication (73%; cyst, endometriosis, benign tumor, inflammation, etc.) and less commonly in conjunction with hysterectomy (61%).
If a BSO is combined with an abdominal hysterectomy (there are different methods of hysterectomy available), the procedure is commonly called a TAH-BSO: total abdominal hysterectomy with a bilateral salpingo-oophorectomy. Sexual intercourse remains possible after salpingectomy, surgical and radiological cancer treatments, and chemotherapy.
Currently, the only intervention proven to reduce ovarian cancer risk is bilateral salpingo-oophorectomy (BSO) at age 35–40 for BRCA1 carriers or age 40–45 for BRCA2, which has been shown to decrease incidence by 80-96%. During BSO both ovaries and both fallopian tubes are removed in one operation.
Oophorectomy (surgical removal of the ovaries) and salpingectomy (surgical removal of the fallopian tubes) are strongly recommended to women with BRCA mutations. [9]: 275–302 Salpingo-oophorectomy is the single most effective method of preventing ovarian and fallopian tube cancer in women with a BRCA mutation.
Prophylactic oophorectomy [ edit ] Prophylactic oophorectomy is the removal of the ovaries and is either done as a planned response to the genetic risk of ovarian or breast cancer, especially among women whom have a hereditary family history of ovarian cancer, have the BRCA1 or BRCA2 mutations, [ 17 ] or have developed breast cancer in the past ...
Bilateral salpingo-oophorectomy (BSO) is the removal of both ovaries and fallopian tubes. According to the ACOG, symptomatic uterine leiomyomas are the most common indication for hysterectomy in the US, followed by abnormal uterine bleeding, endometriosis and prolapse. [ 5 ]
Prophylactic salpingo-oophorectomy is frequently performed in carriers of BRCA1 or BRCA2 mutations, [48] although the benefits conferred by this procedure may vary dependent on the specific mutation. [49] Tubal ligation is a less invasive prophylactic treatment shown to significantly reduce the risk of HGSC. [50]