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  2. AP-1 transcription factor - Wikipedia

    en.wikipedia.org/wiki/AP-1_transcription_factor

    AP-1 was first discovered as a TPA-activated transcription factor that bound to a cis-regulatory element of the human metallothionein IIa promoter and SV40. [3] The AP-1 binding site was identified as the 12-O-Tetradecanoylphorbol-13-acetate response element (TRE) with the consensus sequence 5’-TGA G/C TCA-3’. [4]

  3. Iron condor - Wikipedia

    en.wikipedia.org/wiki/Iron_condor

    The iron condor is an options trading strategy utilizing two vertical spreads – a put spread and a call spread with the same expiration and four different strikes. A long iron condor is essentially selling both sides of the underlying instrument by simultaneously shorting the same number of calls and puts, then covering each position with the purchase of further out of the money call(s) and ...

  4. Biochemical cascade - Wikipedia

    en.wikipedia.org/wiki/Biochemical_cascade

    The basic unit of the Reactome database is a reaction; reactions are then grouped into causal chains to form pathways [115] The Reactome data model allows us to represent many diverse processes in the human system, including the pathways of intermediary metabolism, regulatory pathways, and signal transduction, and high-level processes, such as ...

  5. Cell signaling - Wikipedia

    en.wikipedia.org/wiki/Cell_signaling

    In biology, cell signaling (cell signalling in British English) is the process by which a cell interacts with itself, other cells, and the environment. Cell signaling is a fundamental property of all cellular life in prokaryotes and eukaryotes. Typically, the signaling process involves three components: the signal, the receptor, and the effector.

  6. Upstream and downstream (transduction) - Wikipedia

    en.wikipedia.org/wiki/Upstream_and_downstream...

    The upstream signaling pathway is triggered by the binding of a signaling molecule, a ligand, to a receiving molecule, a receptor. Receptors and ligands exist in many different forms, and only recognize/bond to particular molecules. Upstream extracellular signaling transduce a variety of intracellular cascades. [1]

  7. AOL Mail - AOL Help

    help.aol.com/products/aol-webmail

    Get answers to your AOL Mail, login, Desktop Gold, AOL app, password and subscription questions. Find the support options to contact customer care by email, chat, or phone number.

  8. Crosstalk (biology) - Wikipedia

    en.wikipedia.org/wiki/Crosstalk_(biology)

    The signal transduction pathway begins with ligand-receptor interactions extracellularly. This signal is then transduced through the membrane, stimulating adenylyl cyclase on the inner membrane surface to catalyze the conversion of ATP to cAMP. [3] [4] ERK, a participating protein in the MAPK signaling pathway, can be activated or inhibited by ...

  9. Suppressor of cytokine signalling - Wikipedia

    en.wikipedia.org/wiki/Suppressor_of_cytokine...

    All SOCS have certain structures in common. This includes a varying N-terminal domain involved in protein-protein interactions, a central SH2 domain, which can bind to molecules that have been phosphorylated by tyrosine kinases, and a SOCS box located at the C-terminal that enables recruitment of E3 ligases and ubiquitin signaling molecules.