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Inclusion bodies have a non-unit (single) lipid membrane [citation needed].Protein inclusion bodies are classically thought to contain misfolded protein.However, this has been contested, as green fluorescent protein will sometimes fluoresce in inclusion bodies, which indicates some resemblance of the native structure and researchers have recovered folded protein from inclusion bodies.
Pappenheimer bodies (Peripheral Blood / May-Grünwald Giemsa and Prussian blue stain) Pappenheimer bodies are abnormal basophilic granules of iron found inside red blood cells on routine blood stain. [1] They are a type of inclusion body composed of ferritin aggregates, or mitochondria or phagosomes containing aggregated ferritin. They appear ...
These β4-tetramers accumulate in red blood cells and precipitate to form Hb H inclusion bodies. The inclusion bodies in the mature red blood cells are removed by the spleen and this results in an early destruction of these red blood cells. This destruction of red blood cells by the spleen is termed extravascular hemolysis. [4]
Heinz body stain of feline blood, showing three distinct Heinz bodies. Heinz bodies appear as small round inclusions within the red cell body, though they are not visible when stained with Romanowsky dyes. They are visualized more clearly with supravital staining [5] [6] (e.g., with new methylene blue, crystal violet or bromocresol green).
[2] [better source needed] There are two main kinds of Lewy bodies – classical and cortical. A classical Lewy body is an eosinophilic cytoplasmic inclusion consisting of a dense core surrounded by a halo of 10 nm wide radiating fibrils, the primary structural component of which is alpha-synuclein (α-synuclein).
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Inclusion bodies that when present aid in the diagnosis of conditions of or affecting the human integumentary system Name Composition Location Condition(s) Asteroid: Sporotrichosis: Cowdry A: Herpes simplex: Cowdry B: Polio virus: Donovan: Granuloma inguinale: Dutcher: Intranuclear: Primary cutaneous marginal zone lymphoma Multiple myeloma ...