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Common side effects include heartburn, nausea, indigestion, and abdominal pain. [8] As with other NSAIDs, potential side effects include gastrointestinal bleeding. [10] Long-term use has been associated with kidney failure, and rarely liver failure, and it can exacerbate the condition of patients with heart failure. [8]
The risk and rate of gastric adverse effects is different depending on the type of NSAID medication a person is taking. Indomethacin, ketoprofen, and piroxicam use appear to lead to the highest rate of gastric adverse effects, while ibuprofen (lower doses) and diclofenac appear to have lower rates. [17]
Long-term use of NSAIDs can cause gastric erosions, which can become stomach ulcers and in extreme cases can cause severe haemorrhage, resulting in death. The risk of death as a result of GI bleeding caused by the use of NSAIDs is 1 in 12,000 for adults aged 16–45. [5] The risk increases almost twentyfold for those over 75. [5]
A new study suggests that acetaminophen, also known as Tylenol, can cause complications in some people over age 65. Drs. Marc Siegel and Macie Smith comment on the findings.
These include prescription or OTC medications such as aspirin and ibuprofen (Advil, Motrin IB). ... intense pain on one side of ... changes cause damage to the brain or long-term thinking problems ...
But, technically, if you miss your antidepressant for more than a day, you’d be at risk of side effects, Dr. Gold says. That said, brain zaps generally appear within a few days of stopping your ...
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