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Additional researched vinca alkaloids include vincaminol, vineridine, and vinburnine. Vinpocetine is a semi-synthetic derivative of vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"). [14] Minor vinca alkaloids include minovincine, methoxyminovincine, minovincinine, vincadifformine, desoxyvincaminol, and vincamajine ...
This flourishing culture was the largest known in Europe at that time, extending along the Danube into the Balkans and Central Europe. Thousands of clay statuettes have been discovered in the region's Vinca settlements suggestive of the intense magic-religious practices within the Vinca culture.
Vinca difformis in habitat, Cáceres, Spain. Vinca plants are subshrubs or herbaceous, and have slender trailing stems 1–2 m (3 + 1 ⁄ 2 – 6 + 1 ⁄ 2 ft) long but not growing more than 20–70 cm (8– 27 + 1 ⁄ 2 in) above ground; the stems frequently take root where they touch the ground, enabling the plant to spread widely.
The Vinca massacre (Italian: Eccidio di Vinca) was a massacre carried out near Fivizzano, Tuscany, by the German 16th SS Panzergrenadier Division from 24 to 27 August 1944 in which 162 Italian civilians were killed. It was one of many war crimes the division was involved in while stationed in Italy during the war. [1]
Vinblastine is a vinca alkaloid [9] [2] [10] and a chemical analogue of vincristine. [11] [12] It binds tubulin, thereby inhibiting the assembly of microtubules. [13]Vinblastine treatment causes M phase specific cell cycle arrest by disrupting microtubule assembly and proper formation of the mitotic spindle and the kinetochore, each of which are necessary for the separation of chromosomes ...
The newer semi-synthetic chemotherapeutic agent vinorelbine, used in the treatment of non-small-cell lung cancer, [27] [30] can be prepared either from vindoline and catharanthine [27] [31] or from the vinca alkaloid leurosine, [32] in both cases via anhydrovinblastine. [31] The insulin-stimulating vincoline has been isolated from the plant ...
Alternative names: Turdaş culture Tordos culture: Horizon: First Temperate Neolithic: Period: Neolithic–Chalcolithic: Dates: c. 5400–4500 BC Type site: Vinča-Belo Brdo: Major sites ...
The Vinča houses at Pločnik had stoves and special holes specifically for rubbish, and the dead were buried in cemeteries. People slept on woollen mats and fur and made clothes of wool, flax and leather.