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A later article, independently authored, granted Hogben credit for the principle of using Xenopus to determine gonadotropin levels in a pregnant woman's urine, but not for its usage as a functional pregnancy test. [40] Hormonal pregnancy tests such as Primodos and Duogynon were used in the 1960s and 1970s in the UK and Germany. These tests ...
The Hogben test, named after the British zoologist Lancelot Hogben, was one of the most reliable and rapid pregnancy tests from the 1940s to the 1960s. [6] The urine samples were injected into African clawed frogs. The Hogben test uses female frogs, unlike the Galli-Mainini test which uses male frogs.
It provides the earliest post-implantation test. A meta-analysis published in 2011 found that such tests are reliable more than 98% of the time, as long as they are taken after the seventh week of pregnancy. [1] [2] Chorionic villus sampling (CVS) and amniocentesis are two rather invasive testing procedures. These may, in principle, be ...
The AFP test is often done in the second trimester using the serum from the maternal blood draw. This test looks at a specific protein that is formed in the liver of the fetus and released into the fluid contents of the womb, which is then absorbed into the mother's blood stream. Multiple determinations stem from the results of AFP testing.
A test that says it can detect pregnancy up to six days before a missed period, for example, generally has a lower hCG threshold than one that says it can detect it up to three days before your ...
For example, exposure to a hazard could block ovulation and pregnancy only at specific times of the menstrual cycle. Exposure during the first 3 months of pregnancy might cause a birth defect or a miscarriage. Exposure during the last 6 months of pregnancy could slow the baby's growth, affect its brain development, or cause premature labor. [120]
The rabbit test became a widely used bioassay (animal-based test) to test for pregnancy. The term "rabbit test" was first recorded in 1949, and was the origin of a common euphemism, "the rabbit died", for a positive pregnancy test. [4] The phrase was, in fact, based on a common misconception about the test.
Gravindex is an agglutination inhibition test performed on a urine sample to detect pregnancy. [1] It is based on double antigen antibody reaction. The test detects the prevention of agglutination of HCG -coated latex particles by HCG present in the urine of pregnant women.
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