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  2. Levetiracetam - Wikipedia

    en.wikipedia.org/wiki/Levetiracetam

    Levetiracetam, sold under the brand name Keppra among others, is a novel antiepileptic drug [7] used to treat epilepsy. [8] It is used for partial-onset , myoclonic , or tonic–clonic seizures, [ 7 ] and is taken either by mouth as an immediate or extended release formulation or by injection into a vein .

  3. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    In clinical practice, this means that it takes 4 to 5 times the half-life for a drug's serum concentration to reach steady state after regular dosing is started, stopped, or the dose changed. So, for example, digoxin has a half-life (or t ⁠ 1 / 2 ⁠ ) of 24–36 h; this means that a change in the dose will take the best part of a week to ...

  4. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    The rate at which a drug enters into the body for oral and other extravascular routes. ⁡ 0.693 h −1: Elimination half-‍life: The time required for the concentration of the drug to reach half of its original value.

  5. Elimination rate constant - Wikipedia

    en.wikipedia.org/wiki/Elimination_rate_constant

    The solution of this differential equation is useful in calculating the concentration after the administration of a single dose of drug via IV bolus injection: = C t is concentration after time t; C 0 is the initial concentration (t=0) K is the elimination rate constant

  6. 'Yellowstone,' 'Landman' and the trouble with 'sexy ... - AOL

    www.aol.com/yellowstone-landman-trouble-sexy...

    According to the Hollywood Reporter, in the episode, Beth says to Sadie: “[Travis is] probably the most arrogant man I’ve ever met in my life. Misogynistic. Misogynistic. Condescending.

  7. 2 dead in explosion at manufacturing plant in Louisville ...

    www.aol.com/news/2-dead-explosion-manufacturing...

    Two people were killed and four remain in the hospital from an explosion at a manufacturing facility in Louisville, Kentucky, officials said. The "hazardous materials incident" was reported ...

  8. Half-life - Wikipedia

    en.wikipedia.org/wiki/Half-life

    In this situation it is generally uncommon to talk about half-life in the first place, but sometimes people will describe the decay in terms of its "first half-life", "second half-life", etc., where the first half-life is defined as the time required for decay from the initial value to 50%, the second half-life is from 50% to 25%, and so on.

  9. Gun fished out of creek leads to guilty plea in couple's 2015 ...

    www.aol.com/gun-fished-creek-leads-guilty...

    A man pleaded guilty in the 2015 killings of a Georgia couple after a magnet fisher pulled in a rifle and other evidence linked to the case.