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  2. Your Gout Guide: From Symptoms to Treatment - AOL

    www.aol.com/gout-guide-symptoms-treatment...

    Postmenopausal women have a higher risk of gout. Reproductive factors like starting your ... allopurinol is the first-line medication for lowering uric acid levels. Febuxostat is another uric acid ...

  3. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...

  4. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Levels that cannot be brought below 6.0 mg/dL while attacks continue indicates refractory gout. [68] While historically it is not recommended to start allopurinol during an acute attack of gout, this practice appears acceptable. [69] Allopurinol blocks uric acid production, and is the most commonly used agent. [20]

  5. Managing Out-of-Control Chronic Gout: Going Beyond Oral ...

    www.aol.com/lifestyle/managing-control-chronic...

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  6. Uric acid - Wikipedia

    en.wikipedia.org/wiki/Uric_acid

    Today, inflammation during attacks is more commonly treated with NSAIDs, colchicine, or corticosteroids, and urate levels are managed with allopurinol. [50] Allopurinol, which weakly inhibits xanthine oxidase, is an analog of hypoxanthine that is hydroxylated by xanthine oxidoreductase at the 2-position to give oxipurinol. [51]

  7. Allopurinol hypersensitivity syndrome - Wikipedia

    en.wikipedia.org/wiki/Allopurinol...

    Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...

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