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The thyroid gland secretes three hormones: the two thyroid hormones – triiodothyronine (T 3) and thyroxine (T 4) – and a peptide hormone, calcitonin. The thyroid hormones influence the metabolic rate and protein synthesis and growth and development in children.
Thyroid follicular cells (also called thyroid epithelial cells or thyrocytes [1]) are the major cell type in the thyroid gland, and are responsible for the production and secretion of the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3).
Thyroid hormones (T 4 and T 3) are produced by the follicular cells of the thyroid gland and are regulated by TSH made by the thyrotropes of the anterior pituitary gland. The effects of T 4 in vivo are mediated via T 3 (T 4 is converted to T 3 in target tissues). T 3 is three to five times more active than T 4.
Thyroid gland. follicular cells of the thyroid gland produce and secrete T 3 and T 4 in response to elevated levels of TRH, produced by the hypothalamus, and subsequent elevated levels of TSH, produced by the anterior pituitary gland, which further regulates the metabolic activity and rate of all cells, including cell growth and tissue ...
TSH (with a half-life of about an hour) stimulates the thyroid gland to secrete the hormone thyroxine (T 4), which has only a slight effect on metabolism. T 4 is converted to triiodothyronine (T 3), which is the active hormone that stimulates metabolism. About 80% of this conversion is in the liver and other organs, and 20% in the thyroid itself.
Thyroid stimulating hormone (TSH) is produced by the pituitary gland, another hormone-producing organ in the head. This in turn causes the thyroid to produce T3 and T4, which play a role in the ...
Parafollicular cells, also called C cells, are neuroendocrine cells in the thyroid. They are called C cells because the primary function of these cells is to secrete calcitonin. [1] They are located adjacent to the thyroid follicles and reside in the connective tissue. These cells are large and have a pale stain compared with the follicular cells.
Endocrine glands are ductless glands of the endocrine system that secrete their products, hormones, directly into the blood. The major glands of the endocrine system include the pineal gland , pituitary gland , pancreas , ovaries , testicles , thyroid gland , parathyroid gland , hypothalamus and adrenal glands .