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In type I diabetes, IL-13 antagonized cytotoxic insults to pancreatic β cells enhanced by IL-6. [22] In a mouse model of acetaminophen-induced liver injury eosinophil-driven IL-4/IL-13 mediated hepatoprotective function. [23] In severe alcohol-associated hepatitis low plasma level of IL-13 is a predictor of short-term (90-day) mortality. [24]
The interleukin-13 receptor is a type I cytokine receptor, binding Interleukin-13.It consists of two subunits, encoded by IL13RA1 and IL4R, respectively. [1] [2] These two genes encode the proteins IL-13Rα1 and IL-4Rα.
Interleukin 13 (IL-13) is a pleiotropic cytokine that may be important in the regulation of the inflammatory and immune responses. [40] It inhibits inflammatory cytokine production and synergises with IL-2 in regulating interferon-gamma synthesis. The sequences of IL-4 and IL-13 are distantly related. [41]
Quick hits | Iowa 15, Illinois 13. Tribune. Scott Richey, The News-Gazette, Champaign-Urbana, Ill. November 19, 2023 at 10:48 AM. ... Illinois was this close to a road win Saturday at Iowa. A win ...
Following the breakout success of Boygenius in 2023, and its three members laying relatively low in 2024, Lucy Dacus is the first member of the trio to officially announce a solo album, her first ...
Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (cluster of differentiation 213A2), is a membrane bound protein that in humans is encoded by the IL13RA2 gene. [ 5 ] Function
Hand sanitizer has been seen as a valuable tool in hygiene and illness protection for years. During the height of the COVID-19 pandemic, many people ramped up their use of hand sanitizer, with ...
The effector cytokine which is secreted from IL-33- and STAT5 activator-stimulated Th2 cells is IL-13, which is NF-κB dependent. IL-13 is very similar to IL-4 in amino acid sequence and structure. They also used the same type II IL-4 receptor to activate STAT6. [38] Similar functions have IL-1 to Th17 cells and IL-18 to Th1 lymphocytes.