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[1] [3] Less commonly the lining of the abdomen and rarely the sac surrounding the heart, [11] or the sac surrounding each testis may be affected. [1] [12] Signs and symptoms of mesothelioma may include shortness of breath due to fluid around the lung, a swollen abdomen, chest wall pain, cough, feeling tired, and weight loss. [1]
Amosite and crocidolite are considered the most hazardous asbestos fiber types; [5] however, chrysotile asbestos has also produced tumors in animals and is a recognized cause of asbestosis and malignant mesothelioma in humans, [6] and mesothelioma has been observed in people who were occupationally exposed to chrysotile, family members of the ...
Mesothelioma - A cancer of the mesothelial lining of the lungs and the chest cavity, the peritoneum (abdominal cavity) or the pericardium (a sac surrounding the heart). Unlike lung cancer, mesothelioma has no association with smoking. [14] The only established causal factor is exposure to asbestos or similar fibers. [15]
[1] [9] All types of asbestos fibers are associated with an increased risk. [1] It is generally recommended that currently existing and undamaged asbestos be left undisturbed. [1] Diagnosis is based upon a history of exposure together with medical imaging. [4] Asbestosis is a type of interstitial pulmonary fibrosis. [4] There is no specific ...
Some substances cause cancer primarily through their physical, rather than chemical, effects on cells. [32] A prominent example of this is prolonged exposure to asbestos, naturally occurring mineral fibers which are a major cause of mesothelioma, which is a cancer of the serous membrane, usually the serous membrane surrounding the lungs. [32]
The corresponding relative risk is 1.5 for lung cancer, [81] and 1.9 for prostate cancer. [82] For breast cancer, the relative risk is 1.8 with a first-degree relative having developed it at 50 years of age or older, and 3.3 when the relative developed it when being younger than 50 years of age. [83]
For example, various Global Burden of Disease Studies investigate such factors and quantify recent developments – one such systematic analysis analyzed the (non)progress on cancer and its causes during the 2010–19-decade, indicating that 2019, ~44% of all cancer deaths – or ~4.5 M deaths or ~105 million lost disability-adjusted life years ...
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