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A unicameral bone cyst, also known as a simple bone cyst, is a cavity filled with a yellow-colored fluid. [1] [3] It is considered to be benign since it does not spread beyond the bone. [4] Unicameral bone cysts can be classified into two categories: active and latent. [4]
Some unicameral bone cysts may spontaneously resolve without medical intervention. Specific treatments are determined based on the size of the cyst, the strength of the bone, medical history, extent of the disease, activity level, symptoms an individual is experiencing, and tolerance for specific medications, procedures, or therapies. [3]
Unicameral bone cyst: A solitary bone cyst is a benign non-epithelial bone cavity that is asymptomatic and that is found most commonly in the second decade of life by chance. The long bones are most often affected, but cases involving the jaw bone have been reported. 1 list: Hyperinsulinemic hypoglycemia
The lesion may arise de novo or may arise secondarily within a pre-existing bone tumor, because the abnormal bone causes changes in hemodynamics. An aneurysmal bone cyst can arise from a pre-existing chondroblastoma, a chondromyxoid fibroma, an osteoblastoma, a giant cell tumor, or fibrous dysplasia. A giant cell tumor is the most common cause ...
Simple bone cyst (also termed unicameral bone cysts): A subset of these tumors contain neoplastic cells that express the FUS-NFATC2 or EWSR1-NFATC2 fusion gene. [1] A recent study reported that the neoplastic cells in these cysts expressed a FUS-NFATC2 fusion gene in four and the EWSR1-NFATC2 fusion gene in two of nine test cases.
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Cysts of the jaws are cysts—pathological epithelial-lined cavities filled with fluid or soft material—occurring on the bones of the jaws, the mandible and maxilla.Those are the bones with the highest prevalence of cysts in the human body, due to the abundant amount of epithelial remnants that can be left in the bones of the jaws.
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