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  2. Drug accumulation ratio - Wikipedia

    en.wikipedia.org/wiki/Drug_accumulation_ratio

    The accumulation ratio of a specific drug in humans is determined by clinical studies. According to a 2013 analysis, such studies are typically done with 10 to 20 subjects who are given one single dose followed by a washout phase of seven days , and then seven to 14 repeated doses to reach steady state conditions. Blood samples are drawn 11 ...

  3. Accumulation function - Wikipedia

    en.wikipedia.org/wiki/Accumulation_function

    The accumulation function a(t) is a function defined in terms of time t expressing the ratio of the value at time t (future value) and the initial investment (present value). It is used in interest theory .

  4. Effective half-life - Wikipedia

    en.wikipedia.org/wiki/Effective_half-life

    In pharmacokinetics, the effective half-life is the rate of accumulation or elimination of a biochemical or pharmacological substance in an organism; it is the analogue of biological half-life when the kinetics are governed by multiple independent mechanisms.

  5. Compound interest - Wikipedia

    en.wikipedia.org/wiki/Compound_interest

    Witt's book gave tables based on 10% (the maximum rate of interest allowable on loans) and other rates for different purposes, such as the valuation of property leases. Witt was a London mathematical practitioner and his book is notable for its clarity of expression, depth of insight, and accuracy of calculation, with 124 worked examples. [4] [5]

  6. Doubling time - Wikipedia

    en.wikipedia.org/wiki/Doubling_time

    For example, with an annual growth rate of 4.8% the doubling time is 14.78 years, and a doubling time of 10 years corresponds to a growth rate between 7% and 7.5% (actually about 7.18%). When applied to the constant growth in consumption of a resource, the total amount consumed in one doubling period equals the total amount consumed in all ...

  7. Future value - Wikipedia

    en.wikipedia.org/wiki/Future_value

    Future value is the value of an asset at a specific date. [1] It measures the nominal future sum of money that a given sum of money is "worth" at a specified time in the future assuming a certain interest rate, or more generally, rate of return; it is the present value multiplied by the accumulation function. [2]

  8. Bioconcentration - Wikipedia

    en.wikipedia.org/wiki/Bioconcentration

    [15] k 1 is the rate constant for chemical uptake from water at the respiratory surface (L*kg −1 *d −1). [15] C WD is the chemical concentration dissolved in water (g*L −1 ). [ 15 ] k 2 ,k E ,k G ,k B are rate constants that represent excretion from the organism from the respiratory surface, fecal excretion, metabolic transformation, and ...

  9. Capital accumulation - Wikipedia

    en.wikipedia.org/wiki/Capital_accumulation

    Capital accumulation is the dynamic that motivates the pursuit of profit, involving the investment of money or any financial asset with the goal of increasing the initial monetary value of said asset as a financial return whether in the form of profit, rent, interest, royalties or capital gains.