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Pachygyria, lissencephaly (smooth brain), and polymicrogyria (multiple small gyri) are all the results of abnormal cell migration. The abnormal migration is typically associated with a disorganized cellular architecture, failure to form six layers of cortical neurons (a four-layer cortex is common), and functional problems.
A cerebral AVM is an abnormal anastomosis (connection) between the arteries and veins in the brain due to the lack of a capillary bed, and are most commonly of prenatal origin. [ 10 ] [ 11 ] In normal cerebral circulation , oxygen-enriched blood from the heart travels in sequence through smaller blood vessels going from arteries, to arterioles ...
Brain herniation is a potentially deadly side effect of very high pressure within the skull that occurs when a part of the brain is squeezed across structures within the skull. The brain can shift across such structures as the falx cerebri , the tentorium cerebelli , and even through the foramen magnum (the hole in the base of the skull through ...
The elevated ICP may cause compression of the brain, leading to brain damage and other complications. A complication often overlooked is the possibility of hearing loss due to ICP. The mechanism of ICP on hearing loss is presumed that the transmission of CSF pressure to and from the Perilymphatic space through a patent cochlear aqueduct.
The Ellsworth Howard test (a 10-20 fold increase of urinary cyclic AMP excretion following stimulation with 200 micromoles of parathyroid hormone) may be worth doing also. [citation needed] Serology for toxoplasmosis is also indicated. Brain CT scan is the preferred method of localizing and assessing the extent of cerebral calcifications.
CT scans of the head increase the risk of brain cancer, especially for children. As of 2018, it appeared that there was a risk of one excess cancer per 3,000–10,000 head CT exams in children under the age of 10. [11]
Cisternography is a medical imaging technique to examine the flow of cerebrospinal fluid (CSF) in the brain, and spinal cord. [1] [2] The gold standard for diagnosis of a cranial cerebrospinal fluid leak is CT cisternography. [2] For the diagnosis of a spinal CSF leak radionuclide cisternography also known as radioisotope cisternography is used ...
The sign may be evident on neuroimaging such as CT scanning. [1] The sign is considered ominous because it is commonly associated with a distortion of the brain stem that can cause serious dysfunction evidenced by abnormal posturing and failure of the pupils to constrict in response to light. [1]