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They have been marketed as herbal incense, or "herbal smoking blends", [6] and sold under common names like K2, spice, [8] and synthetic marijuana. [5] They are often labeled "not for human consumption" for liability defense. [ 8 ]
Liquid chromatography (LC) techniques are also possible and, unlike GC methods, can differentiate between the acid and neutral forms of the cannabinoids. There have been systematic attempts to monitor the cannabinoid profile of cannabis over time, but their accuracy is impeded by the illegal status of the plant in many countries.
K2 for one is not a"drug" and it is not a "smoking blend". K2 is a incense that is meant to be used as a incense only. If the owner of the product decides to use this product other then for its intend incense form then it is illegal. Otherwise K2 is a incense and should be used as such. K2 is not meant to be a "smoking" product.
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JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
In the United States, the first restrictions on sale of cannabis came in 1906 (in the District of Columbia). [214] Canada criminalized cannabis in The Opium and Narcotic Drug Act, 1923, [215] before any reports of the use of the drug in Canada, but eventually legalized its consumption for recreational and medicinal purposes in 2018. [16]
The Marburg virus, which causes bleeding from the eyes, nose, and mouth, can be fatal in up to 90% of those infected
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