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Diagram showing the reduction in number of the chromosomes in the process of maturation of the ovum; the process is known as meiosis Main article: Oogenesis The formation of an oocyte is called oocytogenesis, which is a part of oogenesis. [ 1 ]
Oogenesis starts with the process of developing primary oocytes, which occurs via the transformation of oogonia into primary oocytes, a process called oocytogenesis. [11] From one single oogonium, only one mature oocyte will rise, with 3 other cells called polar bodies.
Oocytogenesis : third trimester primary Oocyte: diploid/46: 4C: Ootidogenesis (meiosis 1) (Folliculogenesis) -- polar body separated: Dictyate in prophase I until ovulation secondary Oocyte: haploid/23: 2C: Ootidogenesis (meiosis 2) -- polar body separated: Halted in metaphase II until fertilization Ootid: haploid/23: 1C: Maturation: Minutes ...
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An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries.It secretes hormones that influence stages of the menstrual cycle.In humans, women have approximately 200,000 to 300,000 follicles at the time of puberty, [1] [2] each with the potential to release an egg cell (ovum) at ovulation for fertilization. [3]
The zona pellucida is a translucent matrix of cross-linked glycoprotein filaments that surrounds the mammalian oocyte and is 6.5–20 μm thick depending on the species. Its formation, which depends on a conserved zona pellucida-like (ZP) module that mediates the polymerization of egg coat components, [2] is critical to successful fertilization. [3]
The primary role of the follicle is oocyte support. From the whole pool of follicles a woman is born with, only 0.1% of them will rise ovulation, whereas 99.9% will break down (in a process called follicular atresia).
The anterior pituitary complex and hypophyseal portal system, where FSH and LH are released. Theca cells are responsible for synthesizing androgens, providing signal transduction between granulosa cells and oocytes during development by the establishment of a vascular system, providing nutrients, and providing structure and support to the follicle as it matures.