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Ioannidis describes what he views as some of the problems and calls for reform, characterizing certain points for medical research to be useful again; one example he makes is the need for medicine to be patient-centered (e.g. in the form of the Patient-Centered Outcomes Research Institute) instead of the current practice to mainly take care of ...
Example of direct replication and conceptual replication There are two main types of replication in statistics. First, there is a type called “exact replication” (also called "direct replication"), which involves repeating the study as closely as possible to the original to see whether the original results can be precisely reproduced. [ 3 ]
Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.
The PRISMA flow diagram, depicting the flow of information through the different phases of a systematic review. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) is an evidence-based minimum set of items aimed at helping scientific authors to report a wide array of systematic reviews and meta-analyses, primarily used to assess the benefits and harms of a health care ...
The sharing of research outputs is covered by three standards of the TOPs guidelines: on Data transparency (2), Analytic/code methods transparency (3) and Research materials transparency (4). All the relevant data, code and research materials are to be stored on a "trusted repository" and all analysis being already reproduced independently ...
Brian Nosek of University of Virginia and colleagues sought out to replicate 100 different studies, all published in 2008. [5] The project pulled these studies from three different journals, Psychological Science, the Journal of Personality and Social Psychology, and the Journal of Experimental Psychology: Learning, Memory, and Cognition, published in 2008 to see if they could get the same ...
Main concerns in experimental design include the establishment of validity, reliability, and replicability. For example, these concerns can be partially addressed by carefully choosing the independent variable, reducing the risk of measurement error, and ensuring that the documentation of the method is sufficiently detailed.
The PDF of the essay paper "Why Most Published Research Findings Are False" is a 2005 essay written by John Ioannidis, a professor at the Stanford School of Medicine, and published in PLOS Medicine. [1] It is considered foundational to the field of metascience.