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  2. Acral necrosis - Wikipedia

    en.wikipedia.org/wiki/Acral_necrosis

    Acral necrosis is a symptom common in bubonic plague.The striking black discoloration of skin and tissue, primarily on the extremities ("acral"), is commonly thought to have given rise to the name "Black Death," associated both with the disease and the pandemic which occurred in the 14th century.

  3. Cyanosis - Wikipedia

    en.wikipedia.org/wiki/Cyanosis

    Furthermore, mongolian spots, large birthmarks, and the consumption of food products with blue or purple dyes can also result in the bluish skin tissue discoloration and may be mistaken for cyanosis. [ 2 ] [ 3 ] Appropriate physical examination and history taking is a crucial part to diagnose cyanosis.

  4. Paroxysmal nocturnal hemoglobinuria - Wikipedia

    en.wikipedia.org/wiki/Paroxysmal_nocturnal...

    Danicopan, sold under the brand name Voydeya, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement inhibitor which reversibly binds to factor D to prevent alternative pathway-mediated hemolysis and deposition of complement C3 proteins on red blood cells. The most common side effects include fever, headache, increased levels of liver enzymes (a sign ...

  5. This Chronic Skin Condition Is A Common Cause Of Dark ... - AOL

    www.aol.com/lifestyle/chronic-skin-condition...

    "These creams are usually used once a day at night for 3 months at a time." MelaB3 Serum Intense Anti-Dark Spot Serum ... Clinical Discoloration Repair Serum. amazon.com. $55.00 at amazon.com ...

  6. Drug-induced pigmentation - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_pigmentation

    Purple, red, yellow, slate, or blue-grey pigmented macules on the extremities and trunk – drug eruption: Antimalarials: Blue-ish pigmentation of lower extremities, but can also involve the entire nail bed, nose, cheeks, forehead, ears, and oral mucosa: Psychotropic Drugs: Blue-gray pigmentation on sun-exposed areas Amiodarone

  7. The Sneaky Sign of Inflammation You Shouldn't Ignore - AOL

    www.aol.com/sneaky-sign-inflammation-shouldnt...

    Back pain. When your back aches and there’s no obvious cause (like lifting heavy boxes or falling), inflammation could be the root cause. Inflammatory back pain tends to come on gradually and ...

  8. What is ‘toasted skin syndrome'? Heating pads and blankets ...

    www.aol.com/toasted-skin-syndrome-heating-pads...

    Skin changes can occur after prolonged exposure to any heat source, Camp noted, including laptops, heated car seats, hot water bottles, electric blankets, space heaters and heating pads used to ...

  9. Paroxysmal hand hematoma - Wikipedia

    en.wikipedia.org/wiki/Paroxysmal_hand_hematoma

    Paroxysmal hand hematoma is a skin condition characterized by spontaneous focal hemorrhage into the palm or the volar surface of a finger, which results in transitory localized pain, followed by rapid swelling and localized blueish discoloration.