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Biotin is generally considered safe and well-tolerated when taken in recommended amounts. Because it is a water-soluble vitamin, it isn’t stored in large quantities in the body. So, toxicity is ...
The large intestine microbiota synthesize amounts of biotin estimated to be similar to the amount taken in the diet, and a significant portion of this biotin exists in the free (protein-unbound) form and, thus, is available for absorption. How much is absorbed in humans is unknown, although a review did report that human epithelial cells of the ...
Biotin is an essential B vitamin that helps the body convert food into energy and supports skin and hair health. Add these 7 biotin-rich foods to your diet for benefits.
This high-protein food doubles as a biotin-rich food. One 3-ounce serving of canned tuna (in water) offers up 2% the daily recommended biotin, according to the National Institutes of Health .
Normally, the amount of biotin in the body is regulated by dietary intake, biotin transporters (monocarboxylate transporter 1 and sodium-dependent multivitamin transporter), peptidyl hydrolase biotinidase (BTD), and the protein ligase holocarboxylase synthetase. When any of these regulatory factors are inhibited, biotin deficiency could occur.
Also, multiple biotin molecules can be conjugated to a protein of interest, which allows binding of multiple streptavidin, avidin or neutravidin protein molecules and increases the sensitivity of detection of the protein of interest. There is a large number of biotinylation reagents available that exploit the wide range of possible labelling ...
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Biotinidase Identifiers Symbol BTD NCBI gene 686 HGNC 1122 OMIM 609019 RefSeq NM_000060 UniProt P43251 Other data EC number 3.5.1.12 Locus Chr. 3 p25 Search for Structures Swiss-model Domains InterPro Biotinidase (EC 3.5.1.12, amidohydrolase ...
Biotin deficiency is a relatively uncommon condition, and the vast majority of people can get enough biotin (also known as vitamin B7) just from eating a well-rounded, balanced diet, per Healthline.
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