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Up to 20% of people taking isoniazid experience peripheral neuropathy when taking daily doses of 6 mg/kg of body weight or higher. [26] Gastrointestinal reactions include nausea and vomiting. [ 16 ] Aplastic anemia , thrombocytopenia , and agranulocytosis due to lack of production of red blood cells, platelets, and white blood cells by the bone ...
Ibuprofen, an analgesic and non-steroidal anti-inflammatory drug (NSAID), [1] is sold under many brand-names around the world. The most common are Brufen (its earliest registered trademark), Advil, Motrin, and Nurofen .
In July 2015, Allergan agreed to sell its generic drug business (Actavis Generics [61]) to Teva for $40.5 billion [62] [63] [64] ($33.75 billion in cash and $6.75 billion worth of shares). [65] As a result, Teva dropped its pursuit of Mylan .
It has been suggested that copper complexes of anti-inflammatory drugs are more active than the parent drug [3] and produce fewer gastrointestinal side-effects. [4] In 2008, a United States patent was issued for the utilization of ibuprofenate complexes (including copper ibuprofenate) as a wood preservative .
It combines isoniazid, pyridoxine, sulfamethoxazole, and trimethoprim. [1] Specifically it is used to prevent tuberculosis , toxoplasmosis , pneumonia , malaria , and isosporiasis . [ 2 ] It is taken by mouth .
[citation needed] The drug was approved by the U.S. Food and Drug Administration (FDA) in June 1998. [8] [9] It is made from rifampicin. [medical citation needed] Rifapentine was granted orphan drug designation by the FDA in June 1995, [10] and by the European Commission in June 2010. [11]
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Ibuprofen is a weaker anti-inflammatory agent than other NSAIDs. [10] Ibuprofen was discovered in 1961 by Stewart Adams and John Nicholson [12] while working at Boots UK Limited and initially marketed as Brufen. [13] It is available under a number of brand names including Advil, Motrin, and Nurofen.
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