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In immunology, seroconversion is the development of specific antibodies in the blood serum as a result of infection or immunization, ... (HBeAg) is a sign of current ...
HBeAg is a hepatitis B viral protein, produced by the HBcAg reading frame. It is an indicator of active viral replication ; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious).
The C gene codes for HBeAg and HBcAg. The C gene has a precore and a core region. If translation is initiated at the precore region, the protein product is HBeAg. If translation begins with the core region, HBcAg is the protein product. HBeAg is a marker of HBV replication and infectivity. The precore region is not necessary for viral replication.
HBeAg is produced by proteolytic processing of the pre-core protein. In some rare strains of the virus known as hepatitis B virus precore mutants , no HBeAg is present. [ 45 ] The DNA polymerase is encoded by gene P. Gene S is the gene that codes for the surface antigen (HBsAg).
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HBeAg is produced by proteolytic processing of the pre-core protein. The DNA polymerase is encoded by gene P. Gene S is the gene that codes for the surface antigen (HBsAg). The HBsAg gene is one long open reading frame but contains three in frame "start" (ATG) codons that divide the gene into three sections, pre-S1, pre-S2, and S. Because of ...
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