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Reperfusion therapy is a medical treatment to restore blood flow, either through or around, blocked arteries, typically after a heart attack (myocardial infarction (MI)). Reperfusion therapy includes drugs and surgery. The drugs are thrombolytics and fibrinolytics used in a process called thrombolysis.
A myocardial infarction requires immediate medical attention. Treatment aims to preserve as much heart muscle as possible, and to prevent further complications. [ 28 ] Treatment depends on whether the myocardial infarction is a STEMI or NSTEMI. [ 72 ]
The concept of reperfusion has become so central to the modern treatment of acute myocardial infarction, that we are said to be in the reperfusion era. [ 53 ] [ 54 ] Patients who present with suspected acute myocardial infarction and ST segment elevation (STEMI) or new bundle branch block on the 12 lead ECG are presumed to have an occlusive ...
To address the possibility of identifying and treating asymptomatic coronary artery disease to prevent development of coronary thrombosis, a study published 2018 determined that preemptive treatment with percutaneous coronary intervention did not lead to a difference in death or myocardial infarction over a 15-year period. [13]
A region on chromosome 17 was confined to families with multiple cases of myocardial infarction. [147] Other genome-wide studies have identified a firm risk variant on chromosome 9 (9p21.3). [ 148 ] However, these and other loci are found in intergenic segments and need further research in understanding how the phenotype is affected.
When CABG is performed as an emergency because of a myocardial infarction, the highest priority is to salvage the struggling myocardium. Before operation, an intra-aortic balloon pump (IABP) might be inserted to relieve some of the burden of pumping blood, effectively reducing the amount of oxygen needed by myocardium.
Other strategies: A more recent study proposes that in the case of population with diabetes mellitus—a population particularly at risk—a treatment with paclitaxel-eluting balloon followed by BMS may reduce the incidence of coronary restenosis or myocardial infarction compared with BMS administered alone. [28]
CAD can lead to ischemia (angina pectoris) or infarction (myocardial infarction). Treatment of CAD includes angioplasty, stenting, and coronary artery bypass surgery (CABG). Acute coronary syndrome (ACS) – ACS is a medical emergency and is a broad term encompassing many acute myocardial infarction symptoms. As a syndrome, it consists of a ...
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