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A myxoid tumor is a connective tissue tumor with a "myxoid" background, composed of clear, mucoid substance. [1] Atrial myxoma. This tumoral phenotype is shared by many tumoral entities: Myxomas. Atrial myxoma; Odontogenic myxoma; Cutaneous myxoma; Intramuscular myxoma; Myxoid hamartoma; Aggressive angiomyxoma; Myxoid leiomyoma; Chondromyxoid ...
Myxoma is a rare, benign stromal tumor of mesenchymal origin often confused with other conjunctival stromal tumors. Conjunctival myxomas are thought to originate in Tenon's capsule and can masquerade as conjunctival lymphoma, lymphangioma, ocular surface squamous neoplasia (OSSN), or amelanotic melanoma. [7] Atrial myxoma; Cutaneous myxoma
A thin arborizing vascular network, a large myxoid stroma, mild to moderate cellularity with spindled to stellate cells with little or mild atypia, and the lack of nuclear pleomorphism or mitotic activity are among the histologic markers that are consistently present in cutaneous myxoma.
Alcian blue will give a blue staining to the stromal matrix material. Alcian blue (pH at 2.5) stains the myxoid background material brightly blue in this ectomesenchymal chondromyxoid tumor of the tongue. Mucicarmine will also highlight the stromal matrix (pink). There is a specific recurrent RREB1-MKL2 gene fusion present in these tumors. [8]
The stromal (also called mesenchymal) component often exhibits myxofibrous appearance and in some instances shows chondromatous differentiation. Morphological diversity is the most characteristic feature of this neoplasm. Histologically, it is highly variable in appearance, even within individual tumors.
Phullon means 'leaf' in Greek. It is appropriately named to describe the characteristic papillary projections seen on histology in phyllodes tumors. Phyllodes tumors (from Greek: phullon), are a rare type of biphasic fibroepithelial mass that form from the periductal stromal and epithelial cells of the breast. [1]
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Plexiform angiomyxoid myofibroblastic tumor (PAMT), also called plexiform angiomyxoma, [1] plexiform angiomyxoid tumor, [2] or myxofibroma, [3] is an extremely rare benign mesenchymal myxoid tumor along the gastrointestinal tract.