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2. Sirtuin 4 - Wikipedia

   en.wikipedia.org/wiki/Sirtuin_4

   SIRT4 is a mitochondrial ADP-ribosyltransferase that inhibits mitochondrial glutamate dehydrogenase 1 activity, thereby downregulating insulin secretion in response to amino acids. [7] A deacetylation of malonyl-CoA decarboxylase enzyme by SIRT4 represses the enzyme activity, inhibiting fatty acid oxidation in muscle and liver cells.

3. Penicillamine - Wikipedia

   en.wikipedia.org/wiki/Penicillamine

   Penicillamine is a trifunctional organic compound, consisting of a thiol, an amine, and a carboxylic acid. It is an amino acid structurally similar to cysteine, but with geminal dimethyl substituents α to the thiol. Like most amino acids, it is a colorless solid that exists in the zwitterionic form at physiological pH.

4. Citrullination - Wikipedia

   en.wikipedia.org/wiki/Citrullination

   In rheumatoid arthritis and other autoimmune diseases, such as psoriatic arthritis, systemic lupus erythematosus and Sjögren's syndrome, autoantibodies often attack citrullinated proteins. The presence of anti-citrullinated protein antibody is a standard test for rheumatoid arthritis, and it is associated with more severe disease.

5. Antiarthritics - Wikipedia

   en.wikipedia.org/wiki/Antiarthritics

   Gout is another common type of inflammatory arthritis that typically affects one joint at a time. Pharmacological treatment of gout typically relies on the management of flare-ups. Flare-ups are treated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, steroids, and/or the anti-inflammatory medication colchicine. [4]

6. Rheumatoid arthritis linked to changes in the gut microbiome ...

   www.aol.com/rheumatoid-arthritis-linked-changes...

   As of 2020, about 17.6 million people globally were living with rheumatoid arthritis, an autoimmune disease causing painful inflammation and swelling in joints. Scientists are still not sure as to ...

7. Amino acid - Wikipedia

   en.wikipedia.org/wiki/Amino_acid

   Structure of a typical L-alpha-amino acid in the "neutral" form. Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. [1] Although over 500 amino acids exist in nature, by far the most important are the 22 α-amino acids incorporated into proteins. [2]

8. What Happens to Your Body When You Drink a Glass of Wine ...

   www.aol.com/happens-body-drink-glass-wine...

   If you or someone you know is struggling with alcohol dependence, misuse or addiction, contact the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 800-662 ...

9. Ciclosporin - Wikipedia

   en.wikipedia.org/wiki/Ciclosporin

   Ciclosporin is indicated to treat and prevent graft-versus-host disease in bone marrow transplantation and to prevent rejection of kidney, heart, and liver transplants. [8] [7] It is also approved in the US for treating of rheumatoid arthritis and psoriasis, persistent nummular keratitis following adenoviral keratoconjunctivitis, [25] [7] and as eye drops for treating dry eyes caused by ...