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The resulting test report should specify the assay method and equipment used, and the report of a quantitative test should also provide a reference range for the test result. Many laboratories report reference ranges that are based on all other samples tested in that laboratory, necessarily including samples with abnormal AFP concentrations due ...
The triple test, also called triple screen, the Kettering test or the Bart's test, is an investigation performed during pregnancy in the second trimester to classify a patient as either high-risk or low-risk for chromosomal abnormalities (and neural tube defects). The term "multiple-marker screening test" is sometimes used instead.
Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.
PLAP is a tumor marker, especially in seminoma [8] [9] [10] and ovarian cancer (e.g., dysgerminoma). [11] PLAP is reliable only in non-smokers, as smoking interferes with measurement of PLAP, [12] since serum concentrations of PLAP are increased up to 10-fold in smokers and its measurement is therefore of little value in this group. [13]
No screening test is wholly specific, and a high level of tumor marker can still be found in benign tumors. The only tumor marker currently used in screening is PSA (prostate-specific antigen). Diagnostics; Tumor markers alone can't be used for diagnostic purposes, due to lack of sensitivity and specificity. [5]
Serum tumor marker test: For GTN, the blood is checked for the level of β-hCG, a hormone that is made by the body during pregnancy. β-hCG in the blood of a woman who is not pregnant may be a sign of GTN and also helpful tests to monitor a woman’s recovery during and after treatment. Placental side trophoblastic tumor (PSTT) is ...
Shaina Hurley, who appeared on Season 2 of the Netflix dating series, was diagnosed with cervical cancer while three months pregnant. 'Love is Blind' Star Reveals Shocking Cancer Diagnosis During ...
Immunologic pregnancy tests were introduced in 1960 when Wide and Gemzell presented a test based on in-vitro hemagglutination inhibition. This was a first step away from in-vivo pregnancy testing [42] [43] and initiated a series of improvements in pregnancy testing leading to the contemporary at-home testing. [43]
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