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Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as the sclera. The disease is often contracted through association with other diseases of the body, such as granulomatosis with polyangiitis or rheumatoid arthritis .
Uveitis (/ ˌ juː v i. aɪ t ɪ s /) is inflammation of the uvea, the pigmented layer of the eye between the inner retina and the outer fibrous layer composed of the sclera and cornea. [1] The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris , ciliary body , and choroid .
Patients with episcleritis experience far less photophobia than patients with uveitis. [2] Episcleritis does not cause the presence of cells or flare in the anterior chamber of the eye. [2] In 80 percent of cases, episcleritis affects only one eye, [6] whereas scleritis often affects both eyes.
Inflammation of this layer (uveitis) requires urgent control and is estimated to be responsible for 10% of blindness in the United States. scleritis [ 13 ] – a serious inflammatory condition, often painful, that can result in permanent vision loss, and without an identifiable cause in half of those presenting with it.
(H15.0) Scleritis — a painful inflammation of the sclera (H16) Keratitis — inflammation of the cornea (H16.0) Corneal ulcer / Corneal abrasion — loss of the surface epithelial layer of the eye's cornea (H16.1) Snow blindness / Arc eye — a painful condition caused by exposure of unprotected eyes to bright light
Intermediate uveitis is a form of uveitis localized to the vitreous and peripheral retina. Primary sites of inflammation include the vitreous of which other such entities as pars planitis, posterior cyclitis, and hyalitis are encompassed.
In many cases the cause of panuveitis is unknown. [5] Possible causes include exogenous or endogenous infection, injury, or an autoimmune disease. Endogenous infections caused by syphilis, tuberculosis, mumps, smallpox, influenza, toxoplasmosis, lupus, sarcoidosis, and immune-related inflammations such as Behcet syndrome or Vogt–Koyanagi–Harada disease causes panuveitis.
Scleritis is a serious inflammatory disease of the sclera causing redness of the sclera often progressing to purple. Yellowing or a light green color of the sclera is a visual symptom of jaundice. In cases of osteogenesis imperfecta, the sclera may appear to have a blue tint, more pronounced than the slight blue tint seen in children.