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Magnetic resonance imaging (MRI) scans to assess brain structure, connectivity, and the extent of white matter disease; Positron emission tomography (PET) scans to assess how well the brain uses glucose, and the extent of amyloid plaques and tau tangles. Neuropathological examination if a participant dies and has consented to autopsy.
The diagnostic criteria for depression in Alzheimer disease specify that it requires only 3 of the possible symptoms for major depressive disorder (MDD), rather than the 5 required to diagnose MDD itself, and the symptoms may fluctuate. Therefore, dAD often goes unrecognized within the spectrum of symptoms of Alzheimer's disease. [4]
The hallmark symptom of LATE is a progressive memory loss that predominantly affects short-term and episodic memory. [1] This impairment is often severe enough to interfere with daily functioning and usually remains the chief neurologic deficit, unlike other types of dementia in which non-memory cognitive domains and behavioral changes might be noted earlier or more prominently. [1]
Learning about the dementia stages can help caregivers track and monitor stage-related symptoms to identify a loved one’s brain-health status. The seven stages of dementia include: Stage 1: No ...
Some plaques occur in the brain as a result of aging, but large numbers of plaques and neurofibrillary tangles are characteristic features of Alzheimer's disease. [5] The plaques are highly variable in shape and size; in tissue sections immunostained for Aβ, they comprise a log-normal size distribution curve, with an average plaque area of 400 ...
It's possible that sundowning in dementia patients is caused by a combination of hormonal changes, brain deterioration or damage that has occurred, environmental factors, disruption to a person's ...
A new study found the biggest risk factors and predictors at 60 for dementia at 80. ... But medical specialists who work with dementia patients say the findings are similar to what they see in ...
CT scans can expose patients to levels of radiation 100-500 times higher than traditional x-rays, with higher radiation doses producing better resolution imaging. [37] While easy to use, increases in CT scan use, especially in asymptomatic patients, is a topic of concern since patients are exposed to significantly high levels of radiation. [36]
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