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  2. Antihistamine - Wikipedia

    en.wikipedia.org/wiki/Antihistamine

    The introduction of the first-generation antihistamines marked the beginning of medical treatment of nasal allergies. [28] Research into these drugs led to the discovery that they were H 1 receptor antagonists and also to the development of H 2 receptor antagonists , where H 1 -antihistamines affected the nose and the H 2 -antihistamines ...

  3. Anti-allergic agent - Wikipedia

    en.wikipedia.org/wiki/Anti-allergic_agent

    Third generation antihistamines are metabolites of the second-generation antihistamines but without cardiac toxicity. [8] Indications and route of administration. Antihistamines are generally indicated for the alleviation of conditions such as allergic rhinitis, allergic conjunctivitis, or atopic dermatitis. [9]

  4. H1 antagonist - Wikipedia

    en.wikipedia.org/wiki/H1_antagonist

    The newer, second-generation H 1-antihistamines are far more selective for peripheral histamine H 1-receptors and have a better tolerability profile compared to the first-generation agents. The most common adverse effects noted for second-generation agents include drowsiness, fatigue, headache, nausea and dry mouth. [4]

  5. H3 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H3_receptor_antagonist

    An H 3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H 3 receptors.. Unlike the H 1 and H 2 receptors which have primarily peripheral actions, but cause sedation if they are blocked in the brain, H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of ...

  6. Which Allergy Medicine Is Actually Most Effective? - AOL

    www.aol.com/lifestyle/allergy-medicine-actually...

    “This is a second-generation antihistamine, which is less sedating than the first-generation antihistamines like Benadryl,” says Shaan Waqar, MD, an allergist and immunologist with ENT and ...

  7. Terfenadine - Wikipedia

    en.wikipedia.org/wiki/Terfenadine

    Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was brought to market by Hoechst Marion Roussel (now Sanofi) and was marketed under various brand names, including Seldane in the United States, Triludan in the United Kingdom, and Teldane in Australia. [1]

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