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It is available under a number of brand names including Advil, Motrin, and Nurofen. [ 8 ] [ 14 ] Ibuprofen was first marketed in 1969 in the United Kingdom and in 1974 in the United States. [ 8 ] [ 13 ] It is on the World Health Organization's List of Essential Medicines . [ 15 ]
The list of unapproved chemicals for use as a sleep aid included not only those recommended for banning in 1979, but several others including acetaminophen, aspirin, and passion flower extract. [34] Pharmaceutical manufacturer GlaxoSmithKline owned the Sominex brand in 2011, and announced their decision to divest it in April 2011. [35]
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Advil is primarily a brand of ibuprofen (a pain reliever in the nonsteroidal anti-inflammatory drug category). [1] Advil has been called a "megabrand" because it offers various "products for a wide range of pain, head cold, and sleep problems."
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The patent for Vicoprofen was filed in December 1984, and U.S. patent number 4,587,252 was granted in May 1986. [7] Although ibuprofen and hydrocodone were already available on the market at this time, the fact that they had never been supplied together in a single formulation required approval from the FDA as if it were a new drug.
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