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A homeobox is a DNA sequence, around 180 base pairs long, that regulates large-scale anatomical features in the early stages of embryonic development. Mutations in a homeobox may change large-scale anatomical features of the full-grown organism.
n/a Ensembl ENSG00000185960 n/a UniProt O15266 n/a RefSeq (mRNA) n/a n/a RefSeq (protein) NP_000442 NP_006874 n/a Location (UCSC) n/a n/a PubMed search n/a Wikidata View/Edit Human The short-stature homeobox gene (SHOX), also known as short-stature-homeobox-containing gene, is a gene located on both the X and Y chromosomes, which is associated with short stature in humans if mutated or present ...
Homeobox protein Hox-D13 is a protein that in humans is encoded by the HOXD13 gene. [ 5 ] [ 6 ] [ 7 ] This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms.
Homeobox (Hox) gene expression in Drosophila melanogaster. Drosophila melanogaster is an important model for understanding body plan generation and evolution. The general principles of Hox gene function and logic elucidated in flies will apply to all bilaterian organisms, including humans. Drosophila, like all insects, has eight Hox genes ...
10481 15408 Ensembl ENSG00000159184 ENSMUSG00000049604 UniProt Q92826 P70321 RefSeq (mRNA) NM_006361 NM_008267 RefSeq (protein) NP_006352 NP_032293 Location (UCSC) Chr 17: 48.72 – 48.73 Mb n/a PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-B13 is a protein that in humans is encoded by the HOXB13 gene. Function This gene encodes a transcription factor that belongs ...
3209 15398 Ensembl ENSG00000106031 ENSMUSG00000038203 UniProt P31271 Q62424 RefSeq (mRNA) NM_000522 NM_008264 RefSeq (protein) NP_000513 NP_032290 Location (UCSC) Chr 7: 27.19 – 27.2 Mb Chr 6: 52.23 – 52.24 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A13 is a protein that in humans is encoded by the HOXA13 gene. Function In vertebrates, the genes encoding ...
3207 15396 Ensembl ENSG00000005073 ENSMUSG00000038210 UniProt P31270 P31311 RefSeq (mRNA) NM_005523 NM_010450 RefSeq (protein) NP_005514 NP_034580 Location (UCSC) Chr 7: 27.18 – 27.19 Mb Chr 6: 52.22 – 52.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A11 is a protein that in humans is encoded by the HOXA11 gene. Function In vertebrates, the genes ...
Otx2 is a group of homeobox genes that are typically described as a head organizer in the primitive streak stage of embryonic development. Otx2, which is an encoded protein that plays the role of a transcription factor, has also been shown to be involved in the regional patterning of the midbrain and forebrain.