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Prior to studying medicine, Robert Malone studied computer science at Santa Barbara City College for two years, acting as a teaching assistant in 1981. [2] [8] He received his BS in biochemistry from the University of California, Davis in 1984, his MS in biology from the University of California, San Diego in 1988, and his MD from Northwestern University Feinberg School of Medicine in 1991.
Timeline of some key discoveries and advances in the development of mRNA-based drug technology. The first successful transfection of designed mRNA packaged within a liposomal nanoparticle into a cell was published in 1989. [18] [19] "Naked" (or unprotected) lab-made mRNA was injected a year later into the muscle of mice.
Hoerr did experimental research on the stabilization of messenger ribonucleic acid (mRNA). In 1999, he received his PhD from Günther Jung, Institute of Organic Chemistry, in cooperation with Hans-Georg Rammensee, Institute of Immunology and Cell Biology (both: University of Tübingen) on the topic of RNA vaccines for the induction of specific cytotoxic T lymphocytes (CTL) and antibodies.
Two pioneering scientists who created the technology behind life-saving Covid-19 vaccines have won the Nobel Prize in medicine or physiology.
Initially, MacLachlan and Tekmira turned away from the collaboration. Karikó wanted to team up with Ian MacLachlan because he was the leader of a team that helped advance mRNA technology. Karikó was working on establishing the formulated lipid nanoparticle delivery system that encapsulates mRNA in a dense particle through a mixing process ...
Drew Weissman (born September 7, 1959) is an American physician and immunologist known for his contributions to RNA biology. Weissman is the inaugural Roberts Family Professor in Vaccine Research, director of the Penn Institute for RNA Innovation, and professor of medicine at the Perelman School of Medicine at the University of Pennsylvania (Penn).
While an employee of the NIH, Venter learned how to identify mRNA and began to learn more about those expressed in the human brain. The short cDNA sequence fragments Venter discovered by automated DNA sequencing, he named expressed sequence tags, or ESTs. The NIH Office of Technology Transfer decided to file a patent on the ESTs discovered by ...
Charles Daniel Lane is a British molecular biologist who along with colleagues Gerard Marbaix and John Gurdon discovered the oocyte exogenous mRNA expression system [1] – a system that not only reveals aspects of the control of gene expression but also provides a "living test tube" for the study of macromolecules: such a whole cell system also shows the merits of a non-reductionist approach ...