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The timeline of the COVID-19 pandemic lists the articles containing the chronology and epidemiology of SARS-CoV-2, [1] the virus that causes the coronavirus disease 2019 and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 occurred in Wuhan, People's Republic of China, on or about 17 November 2019. [2]
Cas9 (or "CRISPR-associated protein 9") is an enzyme that uses CRISPR sequences as a guide to recognize and open up specific strands of DNA that are complementary to the CRISPR sequence. Cas9 enzymes together with CRISPR sequences form the basis of a technology known as CRISPR-Cas9 that can be used to edit genes within living organisms.
The history of coronaviruses is an account of the discovery of the diseases caused by coronaviruses and the diseases they cause. It starts with the first report of a new type of upper-respiratory tract disease among chickens in North Dakota, U.S., in 1931.
SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV. [105] Like the SARS-related coronavirus implicated in the 2003 SARS outbreak, SARS‑CoV‑2 is a member of the subgenus Sarbecovirus (beta-CoV lineage B). [106] [107] Coronaviruses undergo frequent recombination. [108]
This article documents the chronology and epidemiology of SARS-CoV-2 in 2019, the virus that causes coronavirus disease 2019 and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 known to have been identified were in Wuhan, Hubei, China, in December 2019.
The world's first COVID-19 drug designed by generative AI is approved for human use, with clinical trials expected to begin in China. The new drug, ISM3312, is developed by Insilico Medicine. [389] A new AI algorithm developed by Baidu is shown to boost the antibody response of COVID-19 mRNA vaccines by 128 times. [390]
The name "coronavirus" is derived from Latin corona, meaning "crown" or "wreath", itself a borrowing from Greek κορώνη korṓnē, "garland, wreath". [8] [9] The name was coined by June Almeida and David Tyrrell who first observed and studied human coronaviruses. [10]
The spread of the JN.1 Omicron variant has led to a surge of COVID-19 cases in New Zealand, resulting in 400 hospitalisations per week and 25 deaths. [340] The JN.1 variant accounted for 14% of sequenced cases reported in New Zealand during the week leading up to 15 December.