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For these purposes PVP-I has been formulated at concentrations of 7.5–10.0% in solution, spray, surgical scrub, ointment, and swab dosage forms; however, use of 10% povidone-iodine though recommended, is infrequently used, as it is poorly accepted by health care workers and is excessively slow to dry.
Iodine is a chemical element with many uses in medicine, depending on the form. Elemental iodine and iodophors are topical antiseptics. [2] Iodine, in non-elemental form, functions as an essential nutrient in human biology (see iodine in biology). [3] Organic compounds containing iodine are also useful iodinated contrast agents in X-ray imaging ...
PVP is a frequently used binder in pharmaceutical tablet formulations. [5] Pharmacokinetic studies in humans and various laboratory animal models indicate no to very little systemic absorption of PVP following oral administration. [6] PVP added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. [7]
Inadine is an iodine-containing non-sticky surgical dressing consisting of a knitted viscose fabric with a polyethylene glycol base that contains and slowly releases the antiseptic povidone-iodine (PVP-1). It is applied to superficial wounds.
iodine preparations, such as iodopovidone in various galenics (ointment, solutions, wound plasters), in the past also Lugol's solution, peroxides such as urea perhydrate solutions and pH-buffered 0.1 – 0.25% peracetic acid solutions, alcohols with or without antiseptic additives, used mainly for skin antisepsis,
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Iodine, especially in the form of povidone-iodine, is widely used because it is well tolerated; does not negatively affect wound healing; leaves a deposit of active iodine, thereby creating the so-called "remnant", or persistent effect; and has wide scope of antimicrobial activity.
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