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AZGP1 is widely expressed in various tissues and body fluids, including the breast, stomach, liver, prostate, plasma, urine, and saliva. [ 7 ] This gene expresses a soluble protein that stimulates lipolysis , induces a reduction in body fat in mice , is associated with the cachexia related to cancer , and is known to be expressed in secretory ...
Zinc transporter ZIP1 is a protein that in humans is encoded by the SLC39A1 gene. [5] [6] [7] The protein ZIP1 is responsible for the active transport of zinc into prostate cells. In many prostate cancers SLC39A1 is silenced causing prostate cancer cells to be low in zinc. [8]
In human prostate cancer, the higher expressing tumors are associated with quicker time to progression and a greater percentage of patients suffering relapse. [ 21 ] [ 22 ] In vitro studies using prostate and breast cancer cell lines with decreased PSMA levels showed a significant decrease in the proliferation, migration, invasion, adhesion and ...
For instance, through activation of ZIP9, testosterone has been found to increase intracellular zinc levels in breast cancer, prostate cancer, and ovarian follicle cells and to induce apoptosis in these cells, an action which may be mediated partially or fully by increased zinc concentrations. [5] [20]
Zinc transporter SLC39A7 (ZIP7), also known as solute carrier family 39 member 7, ... For instance, in prostate cancer, miR-15a-3p targets ZIP7, leading to the ...
These seeds are rich sources of calcium, magnesium, phosphorus, zinc, B vitamins and ALA omega-3s. ... type 2 diabetes and certain types of cancer, including breast and prostate cancer.
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