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While the acronyms are similar, reactive airway disease (RAD) and reactive airways dysfunction syndrome (RADS) are not the same. [1]Reactive airways dysfunction syndrome was first identified by Stuart M. Brooks and colleagues in 1985 as an asthma-like syndrome developing after a single exposure to high levels of an irritating vapor, fume, or smoke.
Reactive airways dysfunction syndrome (RADS) is a severe form of irritant induced asthma where respiratory symptoms usually develop in the minutes or hours after a single accidental inhalation of a high concentration of irritant gas, aerosol, vapor, or smoke. [3]
Stuart Merrill Brooks is an American pulmonary doctor who is credited [1] for discovering and researching Reactive Airways Dysfunction Syndrome (RADS) [2] to describe an asthma-like syndrome developing after a single exposure to high levels of an irritating vapor, fume, or smoke. [3] It involves coughing, wheezing, and dyspnea. [4]
Zafirlukast inhibits the action of CYP3A4, leading to drug-drug interactions with other drugs that are metabolized by CYP3A4. Genetic differences in LTC4 synthase and CYP2C9 may predict how a person reacts to zafirlukast treatment. Zafirlukast (brand name Accolate) was the first cysteinyl leukotriene receptor antagonist approved in the United ...
RAD Reactive airway disease: RIND Reversible ischemic neurologic deficit: RLF Retrolental fibroplasia: RLS Restless legs syndrome: RMDs Repetitive motion disorders: ROP Retinopathy of prematurity: RS Reye's syndrome: RSD Reflex sympathetic dystrophy: RTI Respiratory tract infection: RVF Rift Valley fever
When the airways spasm or constrict in response to the irritating stimulus of the breathing tube, it is difficult to maintain the airway and the patient can become apneic. During general anesthesia, signs of bronchospasm include wheezing, high peak inspiratory pressures, increased intrinsic PEEP , decreased expiratory tidal volumes, and an ...
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Mucoactive drugs include expectorants, mucolytics, mucoregulators, and mucokinetics. These medications are used in the treatment of respiratory diseases that are complicated by the oversecretion or inspissation of mucus. These drugs can be further categorized by their mechanism of action. [1] [2]