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Metronidazole and its metabolites are mainly excreted via the kidneys (77%) and to a lesser extent via the faeces (14%). [ 7 ] [ 8 ] The biological half-life of metronidazole in healthy adults is eight hours, in infants during the first two months of their lives about 23 hours, and in premature babies up to 100 hours.
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
UTI can be categorized into two primary types: cystitis, which refers to lower urinary tract or bladder infection, and pyelonephritis, which indicates upper urinary tract or kidney infection. [1] Escherichia coli (E. Coli) is the predominant microbial trigger of UTIs, accounting for 75% to 95% of reported cases.
17. Kidney Stones. Kidney stones happen when hard deposits of minerals and salts form inside your kidneys, according to the National Kidney Foundation. They can be caused by foods you eat, extra ...
Pyelonephritis is inflammation of the kidney, typically due to a bacterial infection. [3] Symptoms most often include fever and flank tenderness. [2] Other symptoms may include nausea, burning with urination, and frequent urination. [2] Complications may include pus around the kidney, sepsis, or kidney failure. [3]
Kidney failure is known as the end-stage of kidney disease, where dialysis or a kidney transplant is the only treatment option. Chronic kidney disease is defined as prolonged kidney abnormalities (functional and/or structural in nature) that last for more than three months. [ 1 ]
Interstitial nephritis may present with a variety of signs and symptoms, many of these nonspecific. Fever is the most common, occurring in 30-50% of patients, particularly those with drug-induced interstitial nephritis. [2] Other general symptoms that occur with variable frequency include nausea, vomiting, fatigue, lack of appetite, and weight ...
Meghan Markle is opening up about her favorite holiday traditions with her family. In an interview with Marie Claire, the Duchess of Sussex, 43, said, “I love the holidays,” and said of Prince ...
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