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The data seems to point to Staphylococci as the leading bacterial cause of infection leading to ventriculitis being present in about 90% of cases, [4] but generally, what is of more concern is the way the infection entered the ventricles. The brain in its natural state is very protected from infection.
A study by Newman et al. at Duke University Medical Center showed an increased incidence of cognitive decline after coronary artery bypass surgery (CABG), both immediately (53 percent at discharge from hospital) and over time (36 percent six weeks, 24 percent at six months, and 42 percent at five years). [3]
Brain abscess (or cerebral abscess) is an abscess within the brain tissue caused by inflammation and collection of infected material coming from local (ear infection, dental abscess, infection of paranasal sinuses, infection of the mastoid air cells of the temporal bone, epidural abscess) or remote (lung, heart, kidney etc.) infectious sources.
Cerebritis is the inflammation of the cerebrum, which performs a number of important functions, such as memory and speech.It is also defined as a purulent nonencapsulated parenchymal infection of the brain which is characterized by nonspecific features on CT scans (ill-defined low density area with peripheral enhancement) and cannot reliably be distinguished from neoplasms.
The EVD is a foreign body inserted into the brain, and as such it represents a potential portal for serious infection. Historically, the rate of infections associated with EVDs has been very high, ranging from 5% to > 20%. [10] [11] Infections associated with EVDs can progress to become a severe form of brain infection known as ventriculitis.
Not long after, the seizures started up again and the family was told that Caper would need a second surgery to remove more pieces of his brain. “The first surgery had a 60% chance of giving him ...
Lomustine is an alkylating chemotherapy drug that is indicated by the FDA for the treatment of patients with brain tumors (primary and metastatic), following any necessary surgery and radiation, as well as for treatment of progressive Hodgkin’s lymphoma. [8]
Viral encephalitis can occur either as a direct effect of an acute infection, or as one of the sequelae of a latent infection. The majority of viral cases of encephalitis have an unknown cause; however, the most common identifiable cause of viral encephalitis is from herpes simplex infection. [ 12 ]