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  2. Proline organocatalysis - Wikipedia

    en.wikipedia.org/wiki/Proline_organocatalysis

    Proline organocatalysis is the use of proline as an organocatalyst in organic chemistry. This theme is often considered the starting point for the area of organocatalysis, even though early discoveries went unappreciated. [1] Modifications, such as MacMillan’s catalyst and Jorgensen's catalysts, proceed with excellent stereocontrol. [2]: 5574 [3]

  3. Proline - Wikipedia

    en.wikipedia.org/wiki/Proline

    Furthermore, proline is rarely found in α and β structures as it would reduce the stability of such structures, because its side chain α-nitrogen can only form one nitrogen bond. Additionally, proline is the only amino acid that does not form a red-purple colour when developed by spraying with ninhydrin for uses in chromatography. Proline ...

  4. Proline-catalyzed aldol reactions - Wikipedia

    en.wikipedia.org/wiki/Proline-catalyzed_aldol...

    The Hajos–Parrish–Eder–Sauer–Wiechert and Barbas-List [1] reactions in organic chemistry are a family of proline-catalysed asymmetric aldol reactions.. In the 1970s, two research groups discovered (and published) almost simultaneously their discoveries of two related intramolecular reactions: Zoltan Hajos and David Parrish at Hoffmann-La Roche [2] [3] and Rudolf Wiechert et al at ...

  5. Organocatalysis - Wikipedia

    en.wikipedia.org/wiki/Organocatalysis

    In this reaction, naturally occurring chiral proline is the chiral catalyst in an aldol reaction. The starting material is an achiral triketone and it requires just 3% of proline to obtain the reaction product, a ketol in 93% enantiomeric excess. This is the first example of an amino acid-catalyzed asymmetric aldol reaction. [16] [17]

  6. Proline dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/Proline_dehydrogenase

    Other names in common use include L-proline dehydrogenase, L-proline oxidase,and L-proline:(acceptor) oxidoreductase. It employs one cofactor , FAD , which requires riboflavin (vitamin B2). Proline dehydrogenase is in humans encoded by PRODH [ 1 ] and PRODH2 [ 2 ] genes, located on the chromosomes 22 and 19, respectively.

  7. 3 ways to boost longevity in 2025 - AOL

    www.aol.com/3-ways-boost-longevity-2025...

    A modelling study conducted using United States data — published in the British Journal of Sports Medicine in November 2024 — found that, if individuals over 40 walked as much each day as the ...

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