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Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis ... Mechanism of action
Lepetit introduced Rifampicin, an orally active rifamycin, in 1966. [16] Rifabutin, a derivative of rifamycin S, was invented by Italian drug manufacturer Achifar in 1975 and came onto the US market in 1992. [16] Hoechst Marion Roussel (now part of Aventis) introduced rifapentine to the US market in 1998, with Achifar having synthesized it in ...
Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
rifampicin; rifapentine; sulfameter; thalidomide; Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Host defenses are crucial in determining the patient's response to the disease, the clinical presentation, and the bacillary load. These factors also influence the length of therapy and the risk of adverse reactions to ...
Scientists at the Italian drug company Achifar discovered rifabutin in 1975. (Eventually Archifar became part of Farmitalia Carlo Erba, a unit of the conglomerate Montedison which was subsequently bought by Pharmacia) This company's Adria Laboratories subsidiary filed for Food and Drug Administration (FDA) approval of rifabutin under the brand name Mycobutin in the early 1990s and the drug ...
Rifapentine was first synthesized in 1965, by the same company that produced rifampicin. [citation needed] The drug was approved by the U.S. Food and Drug Administration (FDA) in June 1998. [8] [9] It is made from rifampicin. [medical citation needed]
Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis. [1] It is a fixed dose combination of isoniazid and rifampicin (rifampin). [1] It is used together with other antituberculosis medication. [1] It is taken by mouth. [1] It is on the World Health Organization's List of Essential Medicines. [2]
Pyrazinamide is a medication used to treat tuberculosis. [2] For active tuberculosis, it is often used with rifampicin, isoniazid, and either streptomycin or ethambutol. [3] It is not generally recommended for the treatment of latent tuberculosis. [2]