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Curex is an American telehealth company specializing in immunology, specifically the diagnosis and treatment of allergies, including the prescription and delivery of allergy immunotherapy. [1] The company was founded by Gene Kakaulin and Charles Jacoby in 2020 [ 2 ] and is headquartered in New York City. [ 3 ]
Sublingual immunotherapy involves putting drops or a tablet of allergen extracts under the tongue, which are then absorbed through the lining of the mouth. Sublingual immunotherapy has been demonstrated to be effective against rhinoconjunctivitis and asthma symptoms. [15] This effectiveness, however, varies depending on the type of allergen. [15]
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The sublingual route may also be used for vaccines against various infectious diseases. Thus, preclinical studies have found that sublingual vaccines can be highly immunogenic and may protect against influenza virus [4] [5] and Helicobacter pylori, [6] but sublingual administration may also be used for vaccines against other infectious diseases.
Allergen immunotherapy is the only treatment that alters the disease mechanism. [27] Immunotherapy can be administered orally (as sublingual tablets [28] or sublingual drops), or by injections under the skin (subcutaneous). [29] Subcutaneous immunotherapy is the most common form and has the largest body of evidence supporting its effectiveness ...
Areas of research include specific oral tolerance induction (also known as oral immunotherapy), and sublingual immunotherapy. The benefits of allergen immunotherapy for food allergies is unclear, thus is not recommended as of 2015. [7]
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A medical professional applies nose drops. Nasal administration, popularly known as snorting, is a route of administration in which drugs are insufflated through the nose.It can be a form of either topical administration or systemic administration, as the drugs thus locally delivered can go on to have either purely local or systemic effects.